34 Daratumumab Interference With Serum Protein Electrophoresis
نویسندگان
چکیده
منابع مشابه
Interference of monoclonal antibody therapies with serum protein electrophoresis tests.
During routine serum protein electrophoresis (SPE), we recently detected an apparent IgG heavychain immunoglobulin in a 51year-old woman with a 5-year history of IgD multiple myeloma. Other relevant laboratory values at the time included the following: serum creatinine, 159 mol/L (reference interval, 62–97 mol/L); IgG, 2.55 g/L (reference interval, 6.00 – 17.00 g/L); IgM, 0.25 g/L (reference in...
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electrophoresis for detection of DNA point mutations. Journal of Chromatography B 697: 195}205. Righetti PG and GelR C (1998) Analysis of clinicallyrelevant, diagnostic DNA by capillary zone and double-gradient gel slab electrophoresis. Journal of Chromatography A 806: 97}112. Thormann W (1997) Drug monitoring by capillary electrophoresis. In Wong SHY, Sunshine I (Eds) Analytical Therapeutic Dr...
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Two cases are described which show that on urine protein electrophoresis a paraprotein owing to hemoglobin cannot be distinguished from a Bence Jones protein. A simple method is described for confirming the presence of hemoglobin: a densitometric scan of the electrophoretogram at 415 nm, in which hemoglobin absorbs in a band coincident with the restriction. Furthermore, it is shown that other s...
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Semiautomated agarose electrophoresis and immunofixation performed with Hydrasys-Hyrys (Sebia) were compared with conventional, manually performed methods, including cellulose acetate electrophoresis, immunoelectrophoresis, and immunofixation. Reference intervals for agarose electrophoresis with Hydrasys-Hyrys were determined. Within-run imprecision (CV) for fraction quantitation with the semia...
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We compared the automated Paragon 2000 clinical capillary zone electrophoresis (CZE) system with two manual methods, agarose electrophoresis (AGE) and cellulose acetate electrophoresis (CAE). Reference intervals in healthy adults were determined for each method. When compared with AGE and CAE, CZE gave substantially higher reference values for the alpha1-globulin fraction. With CZE, within-run ...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2018
ISSN: 0002-9173,1943-7722
DOI: 10.1093/ajcp/aqx116.033